Home
Resources
Publications
Solid-state Phase Transitions in DL-norvaline Studied by Single-Crystal X-ray Diffraction

Solid-state Phase Transitions in DL-norvaline Studied by Single-Crystal X-ray Diffraction

Carl Henrik Görbitz

J Phys Chem B. 2011 Mar 17;115(10):2447-53.

PMID: 21332110

Abstract:

The amino acid DL-norvaline undergoes two solid-solid phase transitions between room temperature and -180 °C. Single-crystal X-ray diffraction studies show that the first of these transitions, taking place around -80 °C, is completely reversible with respect to crystal quality, whereas the second, taking place below -100 °C, is not due to crystal delamination. High-quality crystal structures were obtained for the higher temperature phase β (at -70 °C) and the intermediate temperature phase α (at -90 °C). They show that although side-chain disorder is present for both forms, the β-to-α phase transition induces significant side-chain rearrangements, which are accompanied by a substantial reduction in molecular volume. The observed polymorphs are compared with those found for DL-aminobutyric acid, DL-norleucine, and DL-methionine.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP760781	DL-Norvaline		760-78-1	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: