Home
Resources
Publications
Sphingosine-1-phosphate Signaling in Blood Pressure Regulation

Sphingosine-1-phosphate Signaling in Blood Pressure Regulation

Suttira Intapad

Am J Physiol Renal Physiol. 2019 Sep 1;317(3):F638-F640.

PMID: 31390266

Abstract:

Sphingolipids were originally believed to play a role only as a backbone of mammalian cell membranes. However, sphingolipid metabolites, especially sphingosine-1-phosphate (S1P), are now recognized as new bioactive signaling molecules that are critically involved in numerous cellular functions of multiple systems including the immune system, central nervous system, and cardiovascular system. S1P research has accelerated in the last decade as new therapeutic drugs have emerged that target the S1P signaling axis to treat diseases of the immune and central nervous systems. There is limited knowledge of the specific effects on cardiovascular disease. This review discusses the current state of knowledge regarding the role of S1P on the regulation of blood pressure, vascular tone, and renal functions.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP26993306	Sphingosine 1-phosphate		26993-30-6	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: