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Structure Determination of Two New Trichothecenes From a Halotolerant Fungus Myrothecium Sp. GS-17 by NMR Spectroscopy

Song-Ya Zhang, Zhan-Lin Li, Li-Ping Guan, Xin Wu, Hua-Qi Pan, Jiao Bai, Hui-Ming Hua

Magn Reson Chem. 2012 Sep;50(9):632-6.

PMID: 22806769

Abstract:

Two new trichothecenes, named 8α-hydroxyroridin H and myrothecin A, along with six known compounds, 8α-acetoxy roridin H, isororidin K, verrucarin A, verrucarin J, verrucarin L and 8α-acetoxy verrucarin L, were isolated from the fermentation broth of a halotolerant fungus Myrothecium sp. GS-17, which was separated from the soil sample of a salina. Structure elucidation and NMR signal assignments were achieved on the basis of spectroscopy. In addition, compounds 1 and 2 were active against plant pathogenic fungi Rhizoctonia solani and Fusarium oxysporum.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP3148092 Verrucarin A from Myrothecium sp. Verrucarin A from Myrothecium sp. 3148-09-2 Price
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