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Studies on a Glucose-Binding Lectin From Peripheral Blood Lymphocytes

R Kayestha, A Berry, K Hajela

Immunol Lett. 1993 Nov;38(3):201-5.

PMID: 8125528

Abstract:

Lectin-carbohydrate interactions have been found to be important in many of the steps of lymphocyte recirculation and inflammatory responses. A D-glucose-specific lectin was isolated from goat peripheral blood lymphocytes by affinity chromatography on N-acetyl-D-glucosamine agarose and gave a single band corresponding to 112 kDa in SDS-PAGE, irrespective of treatment with 2-mercaptoethanol. The lymphocyte lectin agglutinated rabbit and human ABO erythrocytes, the hemagglutinating activity being Ca2+ dependent. It appears to be a member of type C animal lectins.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
IAR42410963 N-Acetyl-D-glucosamine-Agarose N-Acetyl-D-glucosamine-Agarose Price
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