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Synthesis and Applications of α-trifluoromethylated Alkylboron Compounds

O Andreea Argintaru, DaWeon Ryu, Ioana Aron, Gary A Molander

Angew Chem Int Ed Engl. 2013 Dec 16;52(51):13656-60.

PMID: 24214845

Abstract:

RBF3 K is a chemist's BFF: A metal-free synthetic route to unprecedented organoboron compounds bearing an α-trifluoromethyl substituent, employing a variety of trifluoroborate (RBF3 K) starting materials, is reported. These substrates represent the first isolated α-trifluoromethylated alkylboron building blocks, and these reagents lead to a variety of useful bench-stable, synthetic intermediates. Pin=pinacol.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
LS7931444 [(tert-Butylammonio)methyl]trifluoroborate [(tert-Butylammonio)methyl]trifluoroborate Price
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