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Synthesis and Characterization of 4-aryl-4H-chromenes From H-cardanol

Synthesis and Characterization of 4-aryl-4H-chromenes From H-cardanol

Hulluru Surya Prakash Rao, Mani Kamalraj

Nat Prod Commun. 2014 Sep;9(9):1333-40.

PMID: 25918806

Abstract:

We have synthesized and characterized a variety of fat-soluble, low-melting and medicinally useful 4-aryl-4H-chromenes from H-cardanol (side-chain perhydrogenated cardanol, 3-pentadecylphenol), a renewable and low-cost product from locally grown cashew nut trees (Anacardium occidentale L.). We incorporated H-cardanol into the aromatic rings of either 4H-chromene or phenol, or both. Substitution of C4SMe in N-methyl-4-(methylthio)-3-nitro-4H-chromene-2-amines with H-cardanol was regio-specific at the C6 position.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP501246	3-Pentadecylphenol		501-24-6	Price

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