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Synthesis and Properties of Gelatin Methacryloyl (GelMA) Hydrogels and Their Recent Applications in Load-Bearing Tissue

Mingyue Sun, Xiaoting Sun, Ziyuan Wang, Shuyu Guo, Guangjiao Yu, Huazhe Yang

Polymers (Basel). 2018 Nov 21;10(11):1290.

PMID: 30961215

Abstract:

Photocrosslinked gelatin methacryloyl (GelMA) hydrogels have attracted great concern in the biomedical field because of their good biocompatibility and tunable physicochemical properties. Herein, different approaches to synthesize GelMA were introduced, especially, the typical method using UV light to crosslink the gelatin-methacrylic anhydride (MA) precursor was introduced in detail. In addition, the traditional and cutting-edge technologies to characterize the properties of GelMA hydrogels and GelMA prepolymer were also overviewed and compared. Furthermore, the applications of GelMA hydrogels in cell culture and tissue engineering especially in the load-bearing tissue (bone and cartilage) were summarized, followed by concluding remarks.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
LS74888 Gelatin methacryloyl Gelatin methacryloyl Price
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