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Synthesis of Arylacetaldehydes by Iridium-Catalyzed Arylation of Vinylene Carbonate With Arylboronic Acids

Zhe Wang, Fei Xue, Tamio Hayashi

Angew Chem Int Ed Engl. 2019 Aug 5;58(32):11054-11057.

PMID: 31192491

Abstract:

The one-step synthesis of arylacetaldehydes by carbon-carbon bond formation between formylmethyl and aryl groups has been realized by the reaction of vinylene carbonate with arylboronic acids in the presence of an iridium/bisphosphine catalyst and a catalytic amount of tetrahydroxydiboron.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP872366 Vinylene carbonate Vinylene carbonate 872-36-6 Price
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