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Synthesis of [bis(inosine-5')]-tetraphosphate and [bis(inosine-5')]-pentaphosphate Analogues Bearing the Residues of Methylenediphosphonic Acid

Synthesis of [bis(inosine-5')]-tetraphosphate and [bis(inosine-5')]-pentaphosphate Analogues Bearing the Residues of Methylenediphosphonic Acid

A V Shipitsyn, N B Tarussova, E A Shirokova, A A Krayevsky

Nucleosides Nucleotides Nucleic Acids. May-Jun 2000;19(5-6):881-9.

PMID: 10893708

Abstract:

Various methods of synthesis of metabolically stable phosphonate analogues of bisnucleoside oligophosphates containing two residues of methylenediphosphonic acid in the oligophosphate chain are studied. Phosphonate analogues of Ip4I and Ip5I are prepared.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP1984152	Methylenediphosphonic acid		1984-15-2	Price

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