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Synthesis of Both Enantiomers of 12-methyl-13-tridecanolide and 14-methyl-15-pentadecanolide (Muscolide)

Yoshihiro Noda, Natsuki Mamiya, Hitoshi Kashin

Nat Prod Commun. 2013 Jul;8(7):925-8.

PMID: 23980425

Abstract:

Both enantiomers of 12-methyl-13-tridecanolide{(R)-(+)-1, (S)-(-)-1} and 14-methyl-15-pentadecanolide (muscolide) {(R)-(+)-2, (S)-(-)-2} were synthesized from either (S)-(+)- or (R)-(-)-3-bromo-2-methyl-1-propanol 8 as a chiral building block.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP106025 Pentadecanolide Pentadecanolide 106-02-5 Price
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