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Synthesis of C-13-labeled Atrazine

Shuo Chen, Dejie Lin, Zhifu Jiang, Jian Zhao, Beibei Gao, Xiangdong Mei, Jun Ning, Dongmei She

J Labelled Comp Radiopharm. 2013 May 15;56(5):305-6.

PMID: 24285376

Abstract:

Atrazine is a long-lasting herbicide that has been shown to affect hormone levels in amphibians. Using the C-13 labeled atrazine to detect its residue is effective and essential. This study presents three steps for the synthesis of [(13) C3 ]atrazine, which starts from [(13) C]urea, and results in the incorporation of C-13 atoms at the 1, 3 and 5 positions of the S-triazine ring of atrazine. The method prepares the product in an overall yield of 57.6% and chemical purity of 98.6%, for use as an internal standard.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP58069822-A Urea C 13 Urea C 13 58069-82-2 Price
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