0

Synthesis of Gem-Difluorinated Nitroso Compounds

Vladimir O Smirnov, Marina I Struchkova, Dmitry E Arkhipov, Alexander A Korlyukov, Alexander D Dilman

J Org Chem. 2014 Dec 5;79(23):11819-23.

PMID: 25386787

Abstract:

A method for the synthesis of gem-difluorinated nitroso compounds is described. The reaction involves interaction of organozinc reagents with (bromodifluoromethyl)trimethylsilane followed by nitrosation of difluorinated organozinc species with an n-butyl nitrite/chlorotrimethylsilane system.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP115262016 (Bromodifluoromethyl)trimethylsilane (Bromodifluoromethyl)trimethylsilane 115262-01-6 Price
qrcode