Home
Resources
Publications
Synthesis of New Polyether Ether Ketone Derivatives With Silver Binding Site and Coordination Compounds of Their Monomers With Different Silver Salts

Synthesis of New Polyether Ether Ketone Derivatives With Silver Binding Site and Coordination Compounds of Their Monomers With Different Silver Salts

Jérôme Girard, Nathalie Joset, Aurélien Crochet, Milène Tan, Anja Holzheu, Priscilla S Brunetto, Katharina M Fromm

Polymers (Basel). 2016 May 30;8(6):208.

PMID: 30979305

Abstract:

Polyether ether ketone (PEEK) is a well-known polymer used for implants and devices, especially spinal ones. To overcome the biomaterial related infection risks, 4-4'-difluorobenzophenone, the famous PEEK monomer, was modified in order to introduce binding sites for silver ions, which are well known for their antimicrobial activity. The complexation of these new monomers with different silver salts was studied. Crystal structures of different intermediates were obtained with a linear coordination between two pyridine groups and the silver ions in all cases. The mechanical and thermal properties of different new polymers were characterized. The synthesized PEEKN5 polymers showed similar properties than the PEEK ones whereas the PEEKN7 polymers showed similar thermal properties but the mechanical properties are not as good as the ones of PEEK. To improve these properties, these polymers were complexed with silver nitrate in order to "cross-link" with silver ions. The presence of ionic silver in the polymer was then confirmed by thermogravimetric analysis (TGA) and X-ray powder diffraction (XRPD). Finally, a silver-based antimicrobial compound was successfully coated on the surface of PEEKN5.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP345926	4,4′-Difluorobenzophenone		345-92-6	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: