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Synthesis of Tetracyclic Chromenones via platinum(II) Chloride Catalysed Cascade Cyclization of Enediyne-Enones

Mahalingam Sivaraman, Paramasivan T Perumal

Org Biomol Chem. 2014 Feb 28;12(8):1318-27.

PMID: 24435208

Abstract:

PtCl2 catalysed cascade cyclization of an enediyne-enone system to afford a tetracyclic chromenone is reported, which proceeds through two consecutive highly regioselective 6-endo-dig cyclizations in a single step with the formation of two new C-C bonds and two new rings in excellent yield. A mechanism for this transformation is proposed based on the isolated intermediates.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP10025657 Platinum(II) chloride Platinum(II) chloride 10025-65-7 Price
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