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Targeting ALDH2 in Atherosclerosis: Molecular Mechanisms and Therapeutic Opportunities

Sai Ma, Feng Cao

Adv Exp Med Biol. 2019;1193:211-220.

PMID: 31368106

Abstract:

Aldehyde dehydrogenase 2 (ALDH2) is an important member of the functional aldehyde dehydrogenases (ALDHs) family in human beings, playing a fundamental role in the detoxification of acetaldehyde and other aldehydes. In recent years, a number of researches have given attention to the association between ALDH2 and atherosclerosis, which provided insights on targeting ALDH2 for therapeutic intervention of atherosclerosis. In this review, these inspiring studies will be discussed, and the clinical implications and concerns will be expounded.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP1329422265 Phenyl-α-MIDA-boryl aldehyde Phenyl-α-MIDA-boryl aldehyde 1329422-26-5 Price
AP1329422561 4-Tolyl-α-MIDA-boryl aldehyde 4-Tolyl-α-MIDA-boryl aldehyde 1329422-56-1 Price
AP1329422572 4-Fluorophenyl-α-MIDA-boryl aldehyde 4-Fluorophenyl-α-MIDA-boryl aldehyde 1329422-57-2 Price
AP1329422594 Cyclohexyl-α-MIDA-boryl aldehyde Cyclohexyl-α-MIDA-boryl aldehyde 1329422-59-4 Price
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