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TdaA Regulates Tropodithietic Acid Synthesis by Binding to the tdaC Promoter Region

Haifeng Geng, Robert Belas

J Bacteriol. 2011 Aug;193(15):4002-5.

PMID: 21622742

Abstract:

Silicibacter sp. TM1040, a member of the marine Roseobacter clade, produces the antibiotic and quorum signaling molecule tropodithietic acid (TDA), encoded by tdaABCDEF. Here, we showed that an LysR-type transcriptional regulator, TdaA, is a positive regulator of tdaCDE gene expression and binds to the tdaC promoter region.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP750590182 Tropodithietic acid Tropodithietic acid 750590-18-2 Price
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