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Tenascin-C: Form Versus Function

Tenascin-C: Form Versus Function

Sean P Giblin, Kim S Midwood

Cell Adh Migr. 2015;9(1-2):48-82.

PMID: 25482829

Abstract:

Tenascin-C is a large, multimodular, extracellular matrix glycoprotein that exhibits a very restricted pattern of expression but an enormously diverse range of functions. Here, we discuss the importance of deciphering the expression pattern of, and effects mediated by, different forms of this molecule in order to fully understand tenascin-C biology. We focus on both post transcriptional and post translational events such as splicing, glycosylation, assembly into a 3D matrix and proteolytic cleavage, highlighting how these modifications are key to defining tenascin-C function.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
IAR42413303	IGF-Binding Protein 1 human			Price
IAR42415796	Protein Phosphatase Inhibitor 1 human			Price

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