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[The Benzamides Tiapride, Sulpiride, and Amisulpride in Treatment for Tourette's Syndrome]

[The Benzamides Tiapride, Sulpiride, and Amisulpride in Treatment for Tourette's Syndrome]

K R Müller-Vahl

Nervenarzt. 2007 Mar;78(3):264, 266-8, 270-1.

PMID: 16924461

Abstract:

The treatment of Tourette's syndrome is a challenge. Dopamine receptor antagonists are the drugs of first choice for the treatment of tics. Because large controlled trials are lacking, there is no consensus about which of the different neuroleptic drugs should be preferred. In Germany, tiapride seems to be used most often for the treatment of tics in children - although only one small controlled trial has been performed on it till now. In adults, other dopamine receptor antagonists such as risperidone, pimozide, and sulpiride seem to be more effective than tiapride. Today it is unknown whether new atypical neuroleptic drugs including the benzamide amisulpride are more effective than the older benzamides tiapride and sulpiride.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP23672073	(S)-(−)-Sulpiride		23672-07-3	Price

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