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[The Content Determination of Biotransformation of Rb1 in the Total Saponins of Panax Notoginseng by A Plant Endophyte Coniochaeta Sp]

[The Content Determination of Biotransformation of Rb1 in the Total Saponins of Panax Notoginseng by A Plant Endophyte Coniochaeta Sp]

Cong-liang Guo, Xiao-yan Yang, Zi-ming Chen, Shuang Wu, Cheng-xiao Wang, Lu-qi Huang, Xiu-ming Cui

Zhong Yao Cai. 2016 May;39(5):1075-8.

PMID: 30133192

Abstract:

Objective:
To investigate the specific biotransformation product of ginsenoside Rb1 of Panax notoginseng saponins( PNS) by an individual plant endophyte.
Methods:
The endophytes of an invasive plant were selected as the screening targets of active conversion strains. The chromatography and high performance liquid chromatography were used to detemine the metabolite.
Results:
Totally, an active strain of conversion of ginsenoside Rb1 were achieved. The strain can specifically convert ginsenoside Rb1 of PNS to ginsenoside Rd and rare saponin ginsenoside C-K,with the conversion rate of 11. 62% of ginsenoside C-K by fermentation for 12 d.
Conclusion:
This transformation can obviously increase the content of minor ginsenoside C-K in PNS,and it is expected to be a new way to obtain the active saponin ginsenoside C-K in quantity.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP39262141	Ginsenoside C-K		39262-14-1	Price

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