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The First Catalytic Sakurai Reaction of N-alkoxycarbonylamino Sulfones With Allyltrimethylsilane

Thierry Ollevier, Zhiya Li

Org Biomol Chem. 2006 Dec 21;4(24):4440-3.

PMID: 17268636

Abstract:

We report the first catalytic Sakurai reaction of N-alkoxycarbonylamino sulfones with allylsilanes. The allylation reaction of N-alkoxycarbonylamino phenylsulfones with allyltrimethylsilane proceeded smoothly with low catalyst loading of bismuth triflate (2.0 mol%) to afford the corresponding protected homoallylic amines in moderate to very good yields (up to 96%).

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP762721 Allyltrimethylsilane Allyltrimethylsilane 762-72-1 Price
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