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[The Investigation for Lysozyme Conformation Changes in Deuteromethanol Solution by FT-Raman Spectrometer]

B Wang, J Wang, J Yu, H Liu

Guang Pu Xue Yu Guang Pu Fen Xi. 1999 Aug;19(4):535-7.

PMID: 15818948

Abstract:

Lysozyme conformation in deuteromethanol-deuteroxide solution has been studied by FT-Raman spectrometer. By using amide I mode in the Raman spectra and curve fitting method, information of Lysozyme's secondary structure is easily detected in details, and tertiary structure changes can be suggested by relative intensity changes of some bands. It is concluded that lysozyme conformation may be changed to loose structure with incrasing deuteromethanol concentration, and it seems like that increasing loose beta-sheet content lead to the gel's appearing in the solution.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP12168308 Ammonium-d4 deuteroxide solution Ammonium-d4 deuteroxide solution 12168-30-8 Price
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