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The Monohydrates of the Four Polar Dipeptides L-seryl-L-asparagine, L-seryl-L-tyrosine, L-tryptophanyl-L-serine and L-tyrosyl-L-tryptophan

The Monohydrates of the Four Polar Dipeptides L-seryl-L-asparagine, L-seryl-L-tyrosine, L-tryptophanyl-L-serine and L-tyrosyl-L-tryptophan

Carl Henrik Görbitz, Lars Male Hartviksen

Acta Crystallogr C. 2008 Mar;64(Pt 3):o171-6.

PMID: 18322347

Abstract:

The crystal structures of the four dipeptides L-seryl-L-asparagine monohydrate, C(7)H(13)N(3)O(5) x H(2)O, L-seryl-L-tyrosine monohydrate, C(12)H(16)N(2)O(5) x H(2)O, L-tryptophanyl-L-serine monohydrate, C(14)H(17)N(3)O(4) x H(2)O, and L-tyrosyl-L-tryptophan monohydrate, C(20)H(21)N(3)O(4) x H(2)O, are dominated by extensive hydrogen-bonding networks that include cocrystallized solvent water molecules. Side-chain conformations are discussed on the basis of previous observations in dipeptides. These four dipeptide structures greatly expand our knowledge on dipeptides incorporating polar residues such as serine, asparagine, threonine, tyrosine and tryptophan.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP286437125	L-Asparagine-4-13C monohydrate		286437-12-5	Price

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