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The Neurobiology of Borderline Personality Disorder

Maria Mercedes Perez-Rodriguez, Andrea Bulbena-Cabré, Anahita Bassir Nia, Gillian Zipursky, Marianne Goodman, Antonia S New

Psychiatr Clin North Am. 2018 Dec;41(4):633-650.

PMID: 30447729

Abstract:

This article reviews the most salient neurobiological information available about borderline personality disorder (BPD) and presents a theoretic model for what lies at the heart of BPD that is grounded in those findings. It reviews the heritability, genetics, and the biological models of BPD, including the neurobiology of affective instability, impaired interoception, oxytocin and opiate models of poor attachment or interpersonal dysfunction, and structural brain imaging over the course of development in BPD; and posits that the core characteristic of BPD may be an impairment in emotional interoception or alexithymia.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP213481120 BPD BPD 213481-12-0 Price
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