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The Pharmacology of Medications Used in Treating Headache

G D Solomon

Semin Pediatr Neurol. 1995 Jun;2(2):165-77.

PMID: 9422244

Abstract:

Migraine is a common and disabling disease of uncertain pathogenesis. Research on the trigeminovascular system, serotonin receptors, and substance P have provided clues to improving the pharmacotherapy of this disorder. Selective serotonin agonists, such as sumatriptan, dihydroergotamine, ergotamine tartrate, nonsteroidal anti-inflammatory drugs (NSAIDS), isometheptene mucate, and phenothiazines are useful to treat acute attacks. Prophylactic agents include beta-blockers, calcium channel blockers, NSAIDs, antidepressants, and valproate. The addition of several new agents for the acute and prophylactic therapy of migraine has improved the outlook for this debilitating disorder.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP7492311 Isometheptene mucate Isometheptene mucate 7492-31-1 Price
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