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The Preparations of Novel cellulose/phenylboronic Acid Composite Intelligent Bio-Hydrogel and Its Glucose, pH-responsive Behaviors

The Preparations of Novel cellulose/phenylboronic Acid Composite Intelligent Bio-Hydrogel and Its Glucose, pH-responsive Behaviors

Huafeng Peng, Xiaoyu Ning, Gang Wei, Shaopeng Wang, Guoliang Dai, Anqi Ju

Carbohydr Polym. 2018 Sep 1;195:349-355.

PMID: 29804986

Abstract:

Novel intelligent cellulose/4-vinyl-phenylboronic acid (VPBA) composite bio-hydrogels with glucose and pH-responsiveness were successfully prepared via electron beam irradiation technology at room temperature. The composites were characterized by Fourier transform infrared spectrum (FT-IR) and X-ray photoelectron spectroscopy (XPS). The electron beam irradiation results in the appearance of carbonyl in the polymerization of 4-ethenyl-phenylboronic acid, grafting and cross linking reaction in composites, and a novel composite hydrogel was formed between the poly-4-ethenyl-phenylboronic acid and cellulose matrix. By means of the incorporation of phenylboronic acid groups, the composite hydrogels with pH and glucose responsive properties was produced, and glucose responsive properties were investigated by the self-regulation of insulin release of composite hydrogel through a serial glucose solution with different concentrations, which is having great potential applications in many fields.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
LS793678	(3-acetamido-5-carboxy)phenylboronic acid			Price
LS793974	4-(trans-4-Hydroxycyclohexylcarbamoyl)phenylboronic acid			Price

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