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The Safety of Methadone Hydrochloride

John M Swegle, David D Wensel

Expert Opin Drug Saf. 2008 Jan;7(1):5-8.

PMID: 18171310

Abstract:

Methadone is an interesting analgesic for multiple reasons. The unique properties of the agent, low cost and widespread availability have led to increases in methadone prescribing. Despite advantages, methadone is challenging to work with, particularly in patients with high opioid requirements. Recent concerns regarding cardiac arrhythmias and respiratory depression have led to changes in the labeling of methadone. This editorial highlights some of these concerns and provides some recommendations for the appropriate use of methadone in the setting of pain.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP1095905-B (±)-Methadone hydrochloride (±)-Methadone hydrochloride 1095-90-5 Price
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