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[The Structure of Bacillomycin L, an Antibiotic From Bacillus Subtilis (Author's Transl)]

[The Structure of Bacillomycin L, an Antibiotic From Bacillus Subtilis (Author's Transl)]

F Besson, F Peypoux, G Michel, L Delcambe

Eur J Biochem. 1977 Jul 1;77(1):61-7.

PMID: 409602

Abstract:

The structure of bacillomycin L, an antifungal agent isolated from the culture medium of a strain of Bacillus subtilis, has been investigated. The peptide moiety contains one mole each of D-aspartic acid, L-aspartic acid, L-glutamine, L-serine, D-serine, L-threonine, and D-tyrosine. The lipid moiety is a mixture of 3-amino-12-methyltridecanoic acid (46%), 3-amino-12-methyltetradecanoic acid (38%, 3-amino-14-methylpentadecanoic acid (11%), and two minor homologues. The peptide sequence and the cyclic structure were determined by structural analysis of the peptides obtained by mild acid hydrolysis. The molecular weight was determined by the thermoosmotic method; this showed that bacillomycin L has a monomeric structure which is given in Formula 1.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP2724574	12-Methyltridecanoic acid		2724-57-4	Price

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