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Therapeutic Potential of α- And β-Pinene: A Miracle Gift of Nature

Bahare Salehi, Shashi Upadhyay, Ilkay Erdogan Orhan, Arun Kumar Jugran, Sumali L D Jayaweera, Daniel A Dias, Farukh Sharopov, Yasaman Taheri, Natália Martins, Navid Baghalpour, William C Cho, Javad Sharifi-Rad

Biomolecules. 2019 Nov 14;9(11):738.

PMID: 31739596

Abstract:

α- and β-pinene are well-known representatives of the monoterpenes group, and are found in many plants' essential oils. A wide range of pharmacological activities have been reported, including antibiotic resistance modulation, anticoagulant, antitumor, antimicrobial, antimalarial, antioxidant, anti-inflammatory, anti-Leishmania, and analgesic effects. This article aims to summarize the most prominent effects of α- and β-pinene, namely their cytogenetic, gastroprotective, anxiolytic, cytoprotective, anticonvulsant, and neuroprotective effects, as well as their effects against H2O2-stimulated oxidative stress, pancreatitis, stress-stimulated hyperthermia, and pulpal pain. Finally, we will also discuss the bioavailability, administration, as well as their biological activity and clinical applications.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP19902080 (+)-β-Pinene (+)-β-Pinene 19902-08-0 Price
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