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Tolterodine Tartrate

Gennady Ananchenko, Jasmina Novakovic

Profiles Drug Subst Excip Relat Methodol. 2017;42:339-403.

PMID: 28431780

Abstract:

Tolterodine tartrate belongs to the family of muscarinic receptor antagonists and is indicated for the treatment of overactive urinary bladder syndrome. This chapter provides an overview of physical, analytical, and ADME profiles; highlights methods of chemical synthesis; and discusses stability of tolterodine as a free base and/or its l-tartrate salt in solution and in the solid state. The information presented in this chapter is based on the peer-reviewed literature, compendial reports (USP, EP), and authors' data. Patent literature is included only in a few instances.

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