Home
Resources
Publications
Treatment of Drooling With Sublingual Atropine Sulfate in Children and Adolescents With Cerebral Palsy

Treatment of Drooling With Sublingual Atropine Sulfate in Children and Adolescents With Cerebral Palsy

Bruno L Scofano Dias, Alexandre R Fernandes, Heber de S Maia Filho

Arq Neuropsiquiatr. 2017 May;75(5):282-287.

PMID: 28591387

Abstract:

Objective:
To report the effect of sublingual atropine sulfate to treat drooling in children with cerebral palsy by comparing the results of the Drooling Impact Scale in a non-controlled open clinical trial.
Results:
Twenty-five children were assessed. The difference in the mean scores of the pre- and post-treatment scales reached statistical significance. There was a low frequency of side effects compared to studies with other anticholinergics.
Conclusion:
The use of sublingual atropine sulfate seems to be safe and there is a reduction in the Drooling Impact Scale score, which suggests efficacy in the treatment of drooling in children and adolescents with cerebral palsy. Our results should be replicated in randomized, placebo-controlled studies with larger numbers of participants.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP55481	Atropine sulfate		55-48-1	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: