Home
Resources
Publications
Tricalcium phosphate-Fluorapatite as Bone Tissue Engineering: Evaluation of Bioactivity and Biocompatibility

Tricalcium phosphate-Fluorapatite as Bone Tissue Engineering: Evaluation of Bioactivity and Biocompatibility

Rym Taktak, Achwek Elghazel, Jamel Bouaziz, Slim Charfi, Hassib Keskes

Mater Sci Eng C Mater Biol Appl. 2018 May 1;86:121-128.

PMID: 29525087

Abstract:

Biocomposites consisting of β Tricalcium phosphate (β-TCP) with 26.52% Fluorapatite (Fap) were elaborated and characterized in order to evaluate it potential application in bone graft substitute. Bioactivity was determined with in vitro tests by immersion of samples in simulated fluid body for several periods of times. The SEM, EDS and Atomic Absorption Spectroscopy showed the deposition of apatite layer on the surface of samples showing a good bioactivity. However, after 6days of soaking, the dissolution rate of Ca2+ and PO43- decreased which due probably to the improvement of crystallization of the apatite layer. These findings agree with those observed after 6weeks postimplantation of prepared macroporous scaffolds in rabbits. All histological observations of the preliminary in vivo study in the tibia of rabbits proved the biocompatibility and the resorption of the investigated bioceramic. In contrast, the implantation period will have to be optimized by further extensive animal experiments.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP7758874-B	Tricalcium phosphate		7758-87-4	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: