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Two New Phenols From Lysimachia Patungensis

Two New Phenols From Lysimachia Patungensis

Yuan-Yuan Gao, Peng Zeng, Cheng-Lin Jia, Yong Zhang, Teng Zhang, Qi Jia, Yi-Ming Li

J Asian Nat Prod Res. 2017 Jan;19(1):28-34.

PMID: 27308956

Abstract:

Two new phenols, methyl 3-(2-O-β-d-glucopyranosyl-3-hydroxy-5-methoxyphenyl) propionate (1) and myricetin-3,3',5'-tri-O-α-l-rhamnopyranoside (2), together with six known phenols compounds (3-8), were isolated from the whole plant of Lysimachia patungensis Hand.-Mazz. Their structures were elucidated on the basis of the interpretation of spectroscopic data, viz., ESI-MS, HR-TOF-MS, UV, IR, and NMR. All the known phenols were isolated from the genus Lysimachia for the first time. A preliminary bioassay revealed that compounds 3 and 7 exhibited significant protective effects against hydrogen peroxide-induced damage in human retinal endothelial cells (HRECs) with the concentration of 10 μM, respectively. Compound 1 showed moderate activity against the HRECs damage at 100 μM.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP529442-A	Myricetin - CAS 529-44-2		529-44-2	Price

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