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Update on nonoxynol-9 as Vaginal Spermicide

Update on nonoxynol-9 as Vaginal Spermicide

Vidya Iyer, S S Poddar

Eur J Contracept Reprod Health Care. 2008 Dec;13(4):339-50.

PMID: 19117251

Abstract:

Nonoxynol-9 (N-9) is a typical surfactant. For more than 30 years that very property of N-9 has been successfully exploited for its spermicidal action. It is available as an over-the-counter, locally acting vaginal spermicide. The suitability of N-9 as a spermicide is elaborated in this article. The reasons why N-9 may fail as a contraceptive are discussed. In spite of many drawbacks, which are mentioned in the article, N-9 is still often resorted to as a locally acting contraceptive. The review ends with suggestions to alter the molecular structure of N-9 and to adjust the dosages.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP26027383	Nonoxynol 9		26027-38-3	Price

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