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Urinary D-arabinitol/L-arabinitol Levels in Infants Undergoing Long-Term Antibiotic Therapy

Teresa J Stradomska, Bogumila Bobula-Milewska, Anna Bauer, Zbigniew Mielniczuk, Maria Dabkowska, Malgorzata Syczewska, Danuta Dzierzanowska

J Clin Microbiol. 2005 Oct;43(10):5351-4.

PMID: 16208016

Abstract:

Long-term antibiotic therapy is one of the main risk factors for mycosis. The urinary D-arabinitol/L-arabinitol (D-/L-ARA) ratio (a biomarker of several Candida species) was determined by gas chromatography with an electron capture detector in samples from 51 infants undergoing long-term antibiotic therapy. Although 47 of these children had higher D-/L-ARA ratios than healthy controls (P<0.0003), their values nonetheless remained within upper-normal limits (D-/L-ARA ratio of <3.6). Four children with suspected invasive candidiasis had above-normal ratios that normalized with fluconazole treatment.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP7643756-A L-Arabinitol L-Arabinitol 7643-75-6 Price
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