Home
Resources
Publications
Using Small-Molecule Probes to Investigate Aggregation of Sunset Yellow FCF: What Are the Concentration Limits?

Using Small-Molecule Probes to Investigate Aggregation of Sunset Yellow FCF: What Are the Concentration Limits?

Jonathan R Katz, Iain J Day

J Phys Chem B. 2019 Oct 24;123(42):8987-8994.

PMID: 31560194

Abstract:

The assembly of small molecules into larger structures, often driven by noncovalent interactions such as hydrogen bonding, aromatic stacking interactions, and burial of hydrophobic surface, is of widespread interest. The interaction of small molecules with aggregates also has a large range of applications from fluorescence aggregation assays to gas storage in framework materials. Here, we utilize nuclear magnetic resonance spectroscopy to investigate the interaction of a small-molecule probe on the assembly state of sunset yellow across a wide range of relative concentrations. Information from both macroscopic (diffusion) and microscopic (chemical shifts) measurements allows the interaction to be studied and the binding mode to be interrogated. Using fluorophenol as the small-molecule probe, we show that the aggregation behavior of sunset yellow is broadly unaffected by the relative amount of fluorophenol added.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP2783940	Sunset Yellow FCF		2783-94-0	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: