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Validation of Cadmium-Zinc-Telluride Camera for Measurement of Left Ventricular Systolic Performance

Validation of Cadmium-Zinc-Telluride Camera for Measurement of Left Ventricular Systolic Performance

Elisabeth Coupez, Charles Merlin, Viateur Tuyisenge, Laurent Sarry, Bruno Pereira, Jean René Lusson, Louis Boyer, Lucie Cassagnes

J Nucl Cardiol. 2018 Jun;25(3):1029-1036.

PMID: 28194726

Abstract:

Background:
There are paucity of data comparing measurements of left ventricular systolic performance using cadmium-zinc-telluride (CZT) semiconductor cameras with other imaging modalities. This study compared the new system with echocardiography (echo) and cardiac magnetic resonance (CMR) imaging.
Methods:
60 Patients presenting with ST-elevated myocardial infarction (MI) were included. Each patient underwent echo, myocardial perfusion imaging using Spectrum Dynamics D-SPECT(r) (CZT-SPECT), and CMR 6 weeks after MI. The primary endpoint was the agreement between CZT-SPECT and CMR for left ventricular ejection fraction (LVEF) measurement.
Results:
48 of the 60 patients underwent all 3 studies (echo, CMR, and CZT-SPECT) 40 days after admission. CZT-SPECT and CMR LVEF were well correlated (r = .79, P < .0001), as well as CZT-SPECT vs echo and CMR vs echo (r = .79 and .84, respectively, P < .0001). The segmental LV wall thickening and wall motion also showed good concordance between three techniques.
Conclusions:
CZT-SPECT is reliable for LVEF measurement.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP1315113	Zinc telluride		1315-11-3	Price

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