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ε-Viniferin, a Resveratrol Dimer, Prevents Diet-Induced Obesity in Mice

ε-Viniferin, a Resveratrol Dimer, Prevents Diet-Induced Obesity in Mice

Kazuaki Ohara, Kaori Kusano, Sayoko Kitao, Takaaki Yanai, Ryoji Takata, Osamu Kanauchi

Biochem Biophys Res Commun. 2015 Dec 25;468(4):877-82.

PMID: 26596701

Abstract:

Red wines are thought to be one of the major dietary sources of trans-resveratrol. The beneficial effects of t-resveratrol against metabolic disorders have been well characterized, however, red wines also contain various resveratrol derivatives whose health benefits have not been completely elucidated. In this report, we investigated ε-viniferin, a resveratrol dimer, which is present at comparable concentrations to t-resveratrol in red wines, and has higher anti-adipogenesis activity in 3T3-L1 cells. In addition, ε-viniferin was more effective than t-resveratrol in its anti-obesity and anti-inflammatory effects in high-fat diet fed mice. These results suggested ε-viniferin may be one of the active ingredients against metabolic disorders in red wines, in addition to t-resveratrol.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP62218080	ε-Viniferin		62218-08-0	Price

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