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Visible-Light Photoredox/Nickel Dual Catalysis for the Cross-Coupling of Sulfinic Acid Salts With Aryl Iodides

Nai-Wei Liu, Kamil Hofman, André Herbert, Georg Manolikakes

Org Lett. 2018 Feb 2;20(3):760-763.

PMID: 29336160

Abstract:

An efficient cross-coupling of sodium or lithium sulfinates with aryl iodides, using a combination of nickel and photoredox catalysis, is described. The dual catalyst system enables a versatile synthesis of aryl sulfones at room temperature in good yields and displays a broad functional group compatibility. The potential utility of this method in the late-stage diversification of complex molecules and in the conversion of organolithium reagents and sulfur dioxide into sulfones is demonstrated.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP12031651 Lithium nickel dioxide Lithium nickel dioxide 12031-65-1 Price
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