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Ways of Calcium Reabsorption in the Kidney

Matthias B Moor, Olivier Bonny

Am J Physiol Renal Physiol. 2016 Jun 1;310(11):F1337-50.

PMID: 27009338

Abstract:

The role of the kidney in calcium homeostasis has been reshaped from a classic view in which the kidney was regulated by systemic calcitropic hormones such as vitamin D3 or parathyroid hormone to an organ actively taking part in the regulation of calcium handling. With the identification of the intrinsic renal calcium-sensing receptor feedback system, the regulation of paracellular calcium transport involving claudins, and new paracrine regulators such as klotho, the kidney has emerged as a crucial modulator not only of calciuria but also of calcium homeostasis. This review summarizes recent molecular and endocrine contributors to renal calcium handling and highlights the tight link between calcium and sodium reabsorption in the kidney.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP123333802 Sodium acetate-13C2,d3 Sodium acetate-13C2,d3 123333-80-2 Price
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