Home
Resources
Publications
Whey Protein Precludes Lipid and Protein Oxidation and Improves Body Weight Gain in Resistance-Exercised Rats

Whey Protein Precludes Lipid and Protein Oxidation and Improves Body Weight Gain in Resistance-Exercised Rats

Fabiano Kenji Haraguchi, Marcelo Eustáquio Silva, Leandro Xavier Neves, Rinaldo Cardoso dos Santos, Maria Lúcia Pedrosa

Eur J Nutr. 2011 Aug;50(5):331-9.

PMID: 21046124

Abstract:

Background:
Resistance exercise such as weight-lifting (WL) increases oxidation products in plasma, but less is known regarding the effect of WL on oxidative damage to tissues. Dietary compounds are known to improve antioxidant defences. Whey protein (WP) is a source of protein in a variety of sport supplements and can enhance physical performance.
Aim:
To evaluate the effect of WL on biomarkers of lipid and protein oxidation, on liver antioxidants and on muscle growth in the absence or presence of WP in rats.
Methods:
Thirty-two male Fisher rats were randomly assigned to sedentary or exercise-trained groups and were fed with control or WP diets. The WL programme consisted of inducing the animals to perform sets of jumps with weights attached to the chest. After 8 weeks, arteriovenous blood samples, abdominal fat, liver and gastrocnemius muscle were collected for analysis.
Results:
WP precludes WL-mediated increases in muscle protein carbonyl content and maintains low levels of TBARS in exercised and sedentary animals. WL reduced liver CAT activity, whereas WP increased hepatic glutathione content. In addition, WL plus WP generated higher body and muscle weight than exercise without WP.
Conclusions:
These data suggest that WP improves antioxidant defences, which contribute to the reduction of lipid and protein oxidation as well as body and muscle weight gain in resistance-exercised rats.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AS2121318	Oxidation - Reduction - WP			Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: