10-Hydroxywarfarin

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For Research Use Only | Not For Clinical Use
CATAP83219992
CAS83219-99-2
Structure
MDL NumberMFCD00272676
Molecular Weight324.33
InChI KeyBPZSPAZBZFZZBN-UHFFFAOYSA-N
SolubilityDMSO: soluble; methanol: soluble
Colorcolorless
MP183-185 °C
Size5MG, 10MG
Storage Conditions2-8°C

1Chemical Synthesis, Absolute Configuration, and Stereochemistry of Formation of 10-hydroxywarfarin: A Major Oxidative Metabolite of (+)-(R)-warfarin From Hepatic Microsomal Preparations

R F Lawrence, A E Rettie, A C Eddy, W F Trager

Chirality. 1990;2(2):96-105.

PMID: 2400642

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1Cyclodextrin-assisted Enantioseparation of Warfarin and 10-hydroxywarfarin by Capillary Electrophoresis Studied From the Analytical and Thermodynamic Points of View

Paweł Mateusz Nowak, Michał Woźniakiewicz, Paweł Kościelniak

J Pharm Biomed Anal. 2016 Jul 15;126:60-5.

PMID: 27160739

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1Human P450 Metabolism of Warfarin

L S Kaminsky, Z Y Zhang

Pharmacol Ther. 1997;73(1):67-74.

PMID: 9014207

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1In Vitro Stimulation of Warfarin Metabolism by Quinidine: Increases in the Formation of 4'- And 10-hydroxywarfarin

J S Ngui, Q Chen, M Shou, R W Wang, R A Stearns, T A Baillie, W Tang

Drug Metab Dispos. 2001 Jun;29(6):877-86.

PMID: 11353757

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1Regioselectivity Significantly Impacts Microsomal Glucuronidation Efficiency of R/S-6, 7-, and 8-hydroxywarfarin

So-Young Kim, Drew R Jones, Ji-Yeon Kang, Chul-Ho Yun, Grover P Miller

Xenobiotica. 2019 Apr;49(4):397-403.

PMID: 29543105

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