A-1210477

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For Research Use Only | Not For Clinical Use
CATAP1668553261
CAS1668553-26-1
Molecular Weight850.04
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C

1A-1210477, a Selective MCL-1 Inhibitor, Overcomes ABT-737 Resistance in AML

Qing Wang, Siguo Hao

Oncol Lett. 2019 Nov;18(5):5481-5489.

PMID: 31612056

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1Concomitant Targeting of Hedgehog Signaling and MCL-1 Synergistically Induces Cell Death in Hedgehog-driven Cancer Cells

Michael Torsten Meister, Cathinka Boedicker, Benedikt Linder, Donat Kögel, Thomas Klingebiel, Simone Fulda

Cancer Lett. 2019 Nov 28;465:1-11.

PMID: 31465840

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1DRP-1 Is Required for BH3 Mimetic-Mediated Mitochondrial Fragmentation and Apoptosis

Mateus Milani, Dominic P Byrne, Georgia Greaves, Michael Butterworth, Gerald M Cohen, Patrick A Eyers, Shankar Varadarajan

Cell Death Dis. 2017 Jan 12;8(1):e2552.

PMID: 28079887

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1Mcl-1 Inhibitor Suppresses Tumor Growth of Esophageal Squamous Cell Carcinoma in a Mouse Model

Jianqing Lin, Deqiang Fu, Yijun Dai, Jianguang Lin, Tianwen Xu

Oncotarget. 2017 Jun 28;8(70):114457-114462.

PMID: 29383093

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1MCL-1 or BCL-xL-dependent Resistance to the BCL-2 Antagonist (ABT-199) Can Be Overcome by Specific Inhibitor as Single Agents and in Combination With ABT-199 in Acute Myeloid Leukemia Cells

Qing Wang, Jiangbo Wan, Wenhao Zhang, Siguo Hao

Leuk Lymphoma. 2019 Sep;60(9):2170-2180.

PMID: 30626241

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