A-804598

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For Research Use Only | Not For Clinical Use
CATAP1125758851
CAS1125758-85-1
Molecular Weight315.37
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C

1[3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) Is a Novel, Potent, and Selective Antagonist Radioligand for P2X7 Receptors

Diana L Donnelly-Roberts, Marian T Namovic, Bruce Surber, Srirajan X Vaidyanathan, Arturo Perez-Medrano, Ying Wang, William A Carroll, Michael F Jarvis

Neuropharmacology. 2009 Jan;56(1):223-9.

PMID: 18602931

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1A Novel Radioligand for the ATP-gated Ion Channel P2X7: [3H] JNJ-54232334

Brian Lord, Michael K Ameriks, Qi Wang, Lawrence Fourgeaud, Maarten Vliegen, Willy Verluyten, Pieter Haspeslagh, Nicholas I Carruthers, Timothy W Lovenberg, Pascal Bonaventure, Michael A Letavic, Anindya Bhattacharya

Eur J Pharmacol. 2015 Oct 15;765:551-9.

PMID: 26386289

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1P2X7 Receptor Activation Modulates Autophagy in SOD1-G93A Mouse Microglia

Paola Fabbrizio, Susanna Amadio, Savina Apolloni, Cinzia Volonté

Front Cell Neurosci. 2017 Aug 21;11:249.

PMID: 28871219

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1The Impact of the P2X7 Receptor Antagonist A-804598 on Neuroimmune and Behavioral Consequences of Stress

Joseph M Catanzaro, Cara M Hueston, Molly M Deak, Terrence Deak

Behav Pharmacol. 2014 Sep;25(5-6):582-98.

PMID: 25083574

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1The Role of Microglial P2X7: Modulation of Cell Death and Cytokine Release

Yingbo He, Natalie Taylor, Lawrence Fourgeaud, Anindya Bhattacharya

J Neuroinflammation. 2017 Jul 17;14(1):135.

PMID: 28716092

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