BAY 73-6691

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For Research Use Only | Not For Clinical Use

CAT	AP794568926
CAS	794568-92-6
MDL Number	MFCD08705319
Molecular Weight	356.73
InChI Key	FFPXPXOAFQCNBS-MRVPVSSYSA-N

Description	≥98% (HPLC), powder
Solubility	DMSO: >20 mg/mL
Assay	≥98% (HPLC)
Color	off-white
Form	powder
Size	5MG, 25MG
Storage Conditions	2-8°C

1Pharmacological Rescue of Long-Term Potentiation in Alzheimer Diseased Synapses

G Aleph Prieto, Brian H Trieu, Cindy T Dang, Tina Bilousova, Karen H Gylys, Nicole C Berchtold, Gary Lynch, Carl W Cotman

J Neurosci. 2017 Feb 1;37(5):1197-1212.

PMID: 27986924

1Phosphodiesterase 9 (PDE9) Regulates Bovine Tracheal Smooth Muscle Relaxation

Tsuyoshi Tajima, Tamami Shinoda, Norimoto Urakawa, Kazumasa Shimizu, Takeharu Kaneda

J Vet Med Sci. 2018 Mar 24;80(3):499-502.

PMID: 29386424

1Phosphodiesterase-9 (PDE9) Inhibition With BAY 73-6691 Increases Corpus Cavernosum Relaxations Mediated by Nitric Oxide-Cyclic GMP Pathway in Mice

F H da Silva, M N Pereira, C F Franco-Penteado, G De Nucci, E Antunes, M A Claudino

Int J Impot Res. Mar-Apr 2013;25(2):69-73.

PMID: 23034509

1Protective Effects of BAY 73-6691, a Selective Inhibitor of Phosphodiesterase 9, on amyloid-β Peptides-Induced Oxidative Stress in In-Vivo and In-Vitro Models of Alzheimer's Disease

Jian Li, Chun-Na Liu, Ning Wei, Xi-Dong Li, Yuan-Yuan Liu, Rui Yang, Yu-Jie Jia

Brain Res. 2016 Jul 1;1642:327-335.

PMID: 27071547

1The Novel Selective PDE9 Inhibitor BAY 73-6691 Improves Learning and Memory in Rodents

F Josef van der Staay, Kris Rutten, Lars Bärfacker, Jean Devry, Christina Erb, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Marja van Kampen, Arjan Blokland, Jos Prickaerts, Klaus G Reymann, Ulrich H Schröder, etc.

Neuropharmacology. 2008 Oct;55(5):908-18.

PMID: 18674549

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