BMS-986122

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For Research Use Only | Not For Clinical Use
CATAP313669884
CAS313669-88-4
Molecular Weight448.78
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C

1Disruption of the Na+ Ion Binding Site as a Mechanism for Positive Allosteric Modulation of the Mu-Opioid Receptor

Kathryn E Livingston, John R Traynor

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18369-74.

PMID: 25489080

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1Ligand-Based Discovery of a New Scaffold for Allosteric Modulation of the μ-Opioid Receptor

Paola Bisignano, Neil T Burford, Yi Shang, Brennica Marlow, Kathryn E Livingston, Abigail M Fenton, Kristin Rockwell, Lauren Budenholzer, John R Traynor, Samuel W Gerritz, Andrew Alt, Marta Filizola

J Chem Inf Model. 2015 Sep 28;55(9):1836-43.

PMID: 26347990

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1Novel Opioid Receptor Agonists With Reduced Morphine-like Side Effects

Lianghan Zhu, Zhiying Cui, Qihua Zhu, Xiaoming Zha, Yungen Xu

Mini Rev Med Chem. 2018;18(19):1603-1610.

PMID: 30009707

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1Pharmacologic Evidence for a Putative Conserved Allosteric Site on Opioid Receptors

Kathryn E Livingston, M Alexander Stanczyk, Neil T Burford, Andrew Alt, Meritxell Canals, John R Traynor

Mol Pharmacol. 2018 Feb;93(2):157-167.

PMID: 29233847

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