Bortezomib Impurity 19

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For Research Use Only | Not For Clinical Use

CAT	APB03415
Synonyms	(S)-3-methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-1-amine hydrochloride
Molecular Weight	249.58
Molecular Formula	C11H24BNO2·HCl

What is the molecular weight of Bortezomib Impurity 19?

The molecular weight of Bortezomib Impurity 19 is 249.58.

What is the molecular formula of Bortezomib Impurity 19?

The molecular formula of Bortezomib Impurity 19 is C11H24BNO2·HCl.

What are the synonyms of Bortezomib Impurity 19?

One of the synonyms is (S)-3-methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-1-amine hydrochloride.

What is the structure of Bortezomib Impurity 19?

The structure of Bortezomib Impurity 19 is a methyl group attached to a boron atom, with a hydrochloride group attached to the nitrogen.

What is the significance of Bortezomib Impurity 19 in pharmaceutical manufacturing?

Bortezomib Impurity 19 is important in pharmaceutical manufacturing as it is an impurity that can affect the quality and efficacy of the final drug product.

How is Bortezomib Impurity 19 typically identified and quantified in pharmaceutical products?

Bortezomib Impurity 19 is typically identified and quantified using analytical techniques such as HPLC (High Performance Liquid Chromatography) or LC-MS (Liquid Chromatography-Mass Spectrometry).

What are potential risks associated with the presence of Bortezomib Impurity 19 in pharmaceutical products?

The presence of Bortezomib Impurity 19 in pharmaceutical products can lead to decreased drug potency, increased toxicity, and potentially harmful side effects in patients.

How can pharmaceutical manufacturers minimize the presence of Bortezomib Impurity 19 in their products?

Pharmaceutical manufacturers can minimize the presence of Bortezomib Impurity 19 by optimizing their manufacturing processes, conducting thorough quality control testing, and implementing proper storage and handling procedures.

What is the role of regulatory agencies in monitoring the levels of Bortezomib Impurity 19 in pharmaceutical products?

Regulatory agencies set limits on the acceptable levels of Bortezomib Impurity 19 in pharmaceutical products to ensure patient safety and drug efficacy. they also conduct inspections and audits to verify compliance with these regulations.

What are some common methods used to remove or reduce the levels of Bortezomib Impurity 19 in pharmaceutical products during manufacturing?

Common methods used to remove or reduce the levels of Bortezomib Impurity 19 in pharmaceutical products include recrystallization, solvent extraction, and column chromatography.

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