CBR-5884

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For Research Use Only | Not For Clinical Use
CATAP681159273
CAS681159-27-3
Molecular Weight336.39
InChI KeyQBVIRPJBDIZKBC-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpaste
Size5MG, 25MG
Storage Conditions2-8°C

1Disruption of De Novo Serine Synthesis in Müller Cells Induced Mitochondrial Dysfunction and Aggravated Oxidative Damage

Ting Zhang, Mark C Gillies, Michele C Madigan, Weiyong Shen, Jianhai Du, Ulrike Grünert, Fanfan Zhou, Michelle Yam, Ling Zhu

Mol Neurobiol. 2018 Aug;55(8):7025-7037.

PMID: 29383682

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1Identification of a Small Molecule Inhibitor of 3-phosphoglycerate Dehydrogenase to Target Serine Biosynthesis in Cancers

Edouard Mullarky, Natasha C Lucki, Reza Beheshti Zavareh, Justin L Anglin, Ana P Gomes, Brandon N Nicolay, Jenny C Y Wong, Stefan Christen, Hidenori Takahashi, Pradeep K Singh, John Blenis, J David Warren, etc.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1778-83.

PMID: 26831078

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1Inhibition of Serine Metabolism Promotes Resistance to Cisplatin in Gastric Cancer

Xiaoya Zhao, Jianfei Fu, Wanfen Tang, Liangliang Yu, Wenxia Xu

Onco Targets Ther. 2020 May 29;13:4833-4842.

PMID: 32581546

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1Serine-dependent Redox Homeostasis Regulates Glioblastoma Cell Survival

Anna L Engel, Nadja I Lorenz, Kevin Klann, Christian Münch, Cornelia Depner, Joachim P Steinbach, Michael W Ronellenfitsch, Anna-Luisa Luger

Br J Cancer. 2020 Apr;122(9):1391-1398.

PMID: 32203214

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