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For Research Use Only | Not For Clinical Use
Molecular Weight454.75
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Size5MG, 25MG
Storage Conditions2-8°C

1CCG-1423: A Small-Molecule Inhibitor of RhoA Transcriptional Signaling

Chris R Evelyn, Susan M Wade, Qin Wang, Mei Wu, Jorge A Iñiguez-Lluhí, Sofia D Merajver, Richard R Neubig

Mol Cancer Ther. 2007 Aug;6(8):2249-60.

PMID: 17699722

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1Pharmacological Intervention of MKL/SRF Signaling by CCG-1423 Impedes Endothelial Cell Migration and Angiogenesis

David Gau, William Veon, Teresa L Capasso, Ralph Bottcher, Sanjeev Shroff, Beth L Roman, Partha Roy

Angiogenesis. 2017 Nov;20(4):663-672.

PMID: 28638990

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1Rho Signaling Inhibitor, CCG-1423, Inhibits Axonal Elongation and Dendritic Complexity of Rat Cortical Neurons

Keietsu Kikuchi, Jun Shiota, Tetsuya Yamada, Mitsuru Ishikawa, Daisuke Ihara, Mamoru Fukuchi, Masaaki Tsuda, Akiko Tabuchi

Biochem Biophys Res Commun. 2017 Oct 21;492(3):474-479.

PMID: 28830810

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1RPEL Proteins Are the Molecular Targets for CCG-1423, an Inhibitor of Rho Signaling

Ken'ichiro Hayashi, Bunta Watanabe, Yoshiaki Nakagawa, Saki Minami, Tsuyoshi Morita

PLoS One. 2014 Feb 18;9(2):e89016.

PMID: 24558465

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1Stereospecific Inhibitory Effects of CCG-1423 on the Cellular Events Mediated by Myocardin-Related Transcription Factor A

Bunta Watanabe, Saki Minami, Hideaki Ishida, Ryuzo Yoshioka, Yoshiaki Nakagawa, Tsuyoshi Morita, Ken'ichiro Hayashi

PLoS One. 2015 Aug 21;10(8):e0136242.

PMID: 26295164

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