CAS 9004-35-7 Cellulose acetate - Analytical Products / Alfa Chemistry

CAT	APS9004357
CAS	9004-35-7
MDL Number	MFCD00081496
Synonyms	Cellulose acetate, Cellulose Acetate

API Family	Matrix - API Family See respective official monograph(s)
Format	Neat
Shipping	Room Temperature
Storage Conditions	2-8°C Fridge/Coldroom
Subcategory	European Pharmacopoeia (Ph. Eur.)
Type	Excipient

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CAT	Size	Description	Price
AP9004357-1	125MG	United States Pharmacopeia (USP) Reference Standard	Inquiry
AP9004357-2	250G	for column chromatography, SAC 20, acetylated	Inquiry

Case Study

Cellulose Acetate Used for the Preparation of Biochar-Based Slow-Release Nitrogen Fertilizers

Yang, Wanying, et al. International Journal of Biological Macromolecules (2025): 144448.

Cellulose acetate (CA), a biodegradable and cost-effective polymer, was employed for the preparation of a novel slow-release nitrogen fertilizer by coating urea with pinecone biochar (PB) and CA. This strategy addressed the limited nutrient release control of conventional biochar fertilizers.
PB was derived from agricultural waste pinecones via pyrolysis, and the sample prepared at 700 °C (700 PB) exhibited the highest specific surface area (305.35 m²/g), which significantly enhanced the adsorption capacity and coating uniformity. To prepare the composite fertilizer (PBUA), CA was dissolved in acetone to form 5-9 wt% solutions. PB-urea mixtures (PBU0.5, PBU1, PBU1.5) were immersed in CA solution, dried, and further encapsulated with microcrystalline wax using an impregnation method to improve mechanical integrity.
Among various compositions, PBU1.5A9 (mass ratio of PB:urea = 1.5:1; CA = 9 wt%) showed the best sustained nitrogen release performance. Under neutral pH at room temperature, only 4.37% of nitrogen was released within the first 24 h, while 55.63% and 72.56% were released after 28 and 60 days, respectively, complying with national slow-release fertilizer standards. Kinetic modeling indicated the release profile followed the Weibull model.
This study demonstrates the effective application of cellulose acetate as a coating agent in environmentally friendly, biochar-based controlled-release fertilizers, offering promising implications for sustainable agriculture.

Cellulose Acetate Used for the Preparation of Bilayer Indicator Films in Smart Food Packaging

Zhang, Xu, Chunwei Li, and Anning Song. Food Research International (2025): 116585.

Cellulose acetate (CA) was successfully used in the fabrication of an antimicrobial outer layer for bilayer indicator films, designed to enhance food safety monitoring in smart packaging systems. In this study, anthocyanins were chemically stabilized via acylation with maleic anhydride followed by co-pigmentation with tannic acid, significantly improving their thermal, light, and pH stability. These modified anthocyanins were incorporated into a gellan gum (GG)-based inner layer, acting as a pH-responsive indicator.
The outer antimicrobial film was prepared by dissolving 1.5 g of cellulose acetate in tetrahydrofuran (THF), with 1.0 vol% geranyl acetate added to impart antimicrobial functionality. The mixture was homogenized at 50 °C and cast onto glass culture dishes, then dried at 40 °C to form a stable film. Subsequently, the anthocyanin-enriched GG inner solution was layered atop the CA film and dried at room temperature, yielding the final bilayer structure.
Analytical techniques, including SEM, FTIR, and XRD, confirmed the enhanced molecular uniformity and structural integration of the bilayer films. These films exhibited superior optical clarity, mechanical strength, water barrier properties, and color stability. When applied to grass carp packaging, the bilayer films provided real-time freshness monitoring and extended shelf life by 1-2 days.
This study highlights cellulose acetate's role as a functional material for creating active and intelligent food packaging systems.

Cellulose Acetate Used for the Preparation of Graphene-Based Humidity-Sensitive Films

Zhao, Ruiyang, et al. Sensors and Actuators B: Chemical 429 (2025): 137291.

Cellulose acetate, specifically in its water-soluble form (WSCA), was employed as a functional matrix in the preparation of rGO/WSCA composite films for high-performance humidity sensor applications. In this study, WSCA served dual roles: as a humidity-sensitive layer and an effective dispersant to prevent graphene oxide (GO) aggregation during reduction. This approach enabled the construction of an ordered brick-mortar microstructure, imparting the composite film with remarkable mechanical strength (339.5 MPa) and structural integrity.
The fabrication process involved ultrasonic dispersion of GO in water, followed by initial incorporation of WSCA (0.5 mL, 2 wt%) to aid dispersion during GO reduction using hydrazine hydrate. After thermal treatment and cooling, additional WSCA was added to tailor film composition. The final rGO/WSCA films were obtained via vacuum filtration. The optimized film with 5% rGO content, labeled rGO5/WSCA, demonstrated excellent humidity responsiveness.
Thanks to WSCA's abundance of hydroxyl groups, the composite film exhibited rapid response times (within seconds), low hysteresis over a wide relative humidity range (23-97%), and repeatability errors below 2.3% after six cycles. Furthermore, the sensor successfully detected human respiratory patterns under varying conditions, showcasing its potential in non-contact, wearable, and biomedical sensing applications.
This study underscores cellulose acetate's value in producing flexible, sensitive, and stable graphene-based humidity sensors through a facile and scalable method.