CAS 9004-54-0 Dextran - Analytical Products / Alfa Chemistry

CAT	APS9004540
CAS	9004-54-0
MDL Number	MFCD00130935
Synonyms	Gentran 40, Polyglucin, Dextran T 40, G 75,Dextran, Dextran 70, DEX 500, Rondex, Dextran 150, Rheodextran, Dextran D 1390, Dextran 1000, T 70 (carbohydrate), Dextran 75, Dextran T 2000, Dextran T-10, Rheomacrodex, Eudextran, Infucoll, Rheoisodex, Dextran 15, Hemodex, Dextran D 9260, T 5, Dextran B 512, Intradex, T 5 (polysaccharide), Dextran 60, Rheorondex, Rheotran, T 70, LVD, D 1390, Dextran T 10, Onkotin, T 20, Polyglusol, Oncovertin N, T 110, Dextran 40, Dextran PVD, Macrose, Hyskon, Detrax 40, Dextran T 20, T 110 (carbohydrate), Dextran 70, T 10, Dextran T 100, T 500 (carbohydrate), Dextran 2000, Dextran 45, Dextran T 500, Rheopolyglucin, Dextran T 70, Dextran PT 25, Dextran 3000, T 500, Rondex (polysaccharide), Dextran 10, Dextran T 110, Dextran D 10, Dextran 250, Dextranen, Rheopolyglucine, α-Dextran, Dextran 500, T 20 (carbohydrate), T 40 (polysaccharide), T 6, Dextrans (8CI), Longasteril 70, LMD, Dextran PL 1S, Macrodex, Dextran 40000, PL 1S, Expandex, LU 122, Dextran 10000, T 40, Dextran 1.5, T 4, Serva G, Plasmafusin, R-gel, Plavolex, Intrader, Ultradex, D 9260, Dextran RMI, T 4 (polysaccharide), T 150, Hyscon, Plasmodex, Dextran 20000, Dextran B1355, LMWD, Gentran, Dextran T 150, Dextraven, T 10 (carbohydrate), T 250 (polysaccharide), Promit, T 250, Dextran 110
EC Number	232-677-5
InChI	InChI=1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

API Family	Matrix - API Family See respective official monograph(s)
Format	Neat
Linear Formula	[C6H10O5]n
Shipping	Room Temperature
Storage Conditions	2-8°C Fridge/Coldroom
Subcategory	European Pharmacopoeia (Ph. Eur.)
Type	Excipient

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CAT	Size	Form	Description	Price
AP9004540-B1	100MG, 500MG	powder or crystals; Mp ~4,440; Mw ~5,220	analytical standard, for GPC, 5,000	Inquiry
AP9004540-B2	500MG	powder or crystals; Mp ~1,080; Mw ~1,270	analytical standard, for GPC, 1,000	Inquiry
AP9004540-B3	100MG, 500MG	powder or crystals; Mp ~9,890; Mw ~11,600	analytical standard, for GPC, 12,000	Inquiry
AP9004540-B4	100MG	powder or crystals; Mp ~21,400; Mw ~23,800	analytical standard, for GPC, 25,000	Inquiry
AP9004540-B5	100MG	powder or crystals; Mp ~43,500; Mw ~48,600	analytical standard, for GPC, 50,000	Inquiry
AP9004540-B6	100MG	powder or crystals; Mp ~66,700; Mw ~80,900	analytical standard, for GPC, 80,000	Inquiry
AP9004540-B7	100MG	crystalline; Mp ~123,600; Mw ~147,600	analytical standard, for GPC, 150,000	Inquiry
AP9004540-B8	100MG, 500MG	powder or crystals; Mp ~196,300; Mw ~273,000	analytical standard, for GPC, 270,000	Inquiry
AP9004540-B9	100MG	powder or crystals; Mp ~276,500; Mw ~409,800	analytical standard, for GPC, 410,000	Inquiry
AP9004540-B10	100MG	powder or crystals; Mp ~401,300; Mw ~667,800	analytical standard, for GPC, 670,000	Inquiry
AP9004540-B11	5G, 25G, 100G	powder	enzymatic synth.	Inquiry

Case Study

Dextran Used for the Preparation of Ultrasound-Assisted Quinoa Protein-Dextran Conjugates via the Maillard Reaction

Feng, Jingzhao, et al. Food Chemistry 478 (2025): 143601.

Dextran (DX), a natural polysaccharide, was employed in this study to prepare quinoa protein-dextran (QP-DX) conjugates via the Maillard reaction under ultrasound treatment, aiming to enhance the functional properties of quinoa protein for food emulsification applications.
DX of varying molecular weights (10, 40, and 70 kDa) was grafted onto quinoa protein (QP) at pH 9 and 70 °C, using ultrasound powers ranging from 100 to 300 W. Structural characterization revealed that DX covalently bonded to QP, particularly the 11S globulin and B subunits, leading to significant conformational changes from ordered structures to β-turn and random coil. Among all samples, the conjugate synthesized with 40 kDa DX at 200 W exhibited the highest grafting degree (28.6%), smallest particle size (91.01 nm), and most negative zeta potential (-39.3 mV).
This optimized QP-DX conjugate also demonstrated a low interfacial tension (7.8 mN/m), indicative of improved amphiphilic properties and steric stabilization. When applied to oil-in-water emulsions, it produced stable systems with finely dispersed droplets and excellent resistance to creaming and aggregation over time.
This work highlights DX's critical role in tuning protein structure and interfacial activity, showcasing its application in the preparation of advanced food-grade emulsifiers. The Maillard reaction, enhanced by ultrasound, offers a promising route for the functional modification of plant proteins using dextran.

Dextran Used for the Preparation of Pyrogallol-Conjugated Hydrogels via Hantzsch Cross-Linking Reaction

Du, Y., Xu, Y., Hou, J., Li, X., Yang, J., Yang, J., ... & Su, H. (2025). Separation and Purification Technology, 132098.

Dextran (DX) was utilized as the core scaffold for the synthesis of pyrogallol-functionalized hydrogels (PYG@Dex) through a multi-step, precisely controlled experimental process. Initially, β-ketoester groups were grafted onto dextran by transesterification with tert-butyl acetoacetate (t-BAA). Specifically, dextran (4.0 g) was dissolved in 50 mL DMSO, and varying molar ratios of t-BAA (based on the anhydroglucose unit, AGU) were added. The mixture was stirred at 110 °C for 2 h, and the product (Dex-g-BAAm) was recovered via ethanol precipitation and drying.
For hydrogel formation, the Hantzsch cross-linking reaction was employed. Aqueous solutions of Dex-g-BAAm (150 mg/mL), NH₄OAc (800 mg/mL), and 3,4,5-trihydroxybenzaldehyde in methanol (250 mg/mL) were combined in a molar ratio of β-ketoester:aldehyde:NH₄OAc = 2:2:2. The reaction proceeded at room temperature for 4 h, forming hydrogels through the in situ generation of 1,4-dihydropyridine cross-links. The resulting PYG@Dex gels were washed with methanol and deionized water, followed by freeze-drying.
This stepwise protocol enabled efficient incorporation of polyphenolic pyrogallol moieties into the dextran network, forming antioxidant-rich hydrogels with potential for hemoperfusion. The methodology highlights dextran's excellent reactivity and processability in hydrogel-based biomedical applications.

Dextran Used for the Preparation of Antifreeze Glycopeptides via Maillard Reaction for Frozen Food Preservation

Jiang, Ziwei, et al. Journal of Future Foods (2025).

Dextran was employed as a glycosylation agent in the synthesis of antifreeze glycopeptides (GCSPs) through the Maillard Reaction (MR) with crayfish shell-derived peptides (CSPs), yielding a novel cryoprotective agent with both functional and sensory enhancements. CSPs and dextran were reacted under optimized aqueous conditions (pH 8.0, 50 °C) for 60 minutes, with varying mass ratios. The resulting GCSPs featured covalent C-N and C-O linkages, as confirmed by infrared and fluorescence spectroscopy, and exhibited significantly increased molecular weight and structural compactness.
The GCSPs demonstrated superior thermal hysteresis (1.23 °C) and a lower glass transition temperature (-19.5 °C), indicative of enhanced antifreeze performance. Thermogravimetric analysis revealed improved thermal stability post-glycosylation. Importantly, MR-induced formation of pyran derivatives and aldehydes mitigated CSPs' fishy odor, producing a more acceptable aroma profile.
Functionally, GCSPs reduced water loss and improved water-holding capacity in frozen pork, enhancing texture parameters such as firmness and chewiness. Low-field NMR confirmed their role in retaining free water and maintaining moisture stability during thawing.
This study highlights dextran's versatility in food applications, particularly its role in creating bioactive glycopeptides with cryoprotective, antioxidant, and flavor-modifying properties. The resulting GCSPs offer promising utility in frozen food preservation, exemplifying dextran's efficacy in biopolymer-based functional material development.